What is intermittent claudication?

Peripheral arterial disease (PAD) is a chronic condition caused by atherosclerotic narrowing and blocking of the peripheral arteries. This results in limitation of blood supply to the muscles and therefore pain when exercising. The most common manifestation of PAD is intermittent claudication (IC), which is marked by exertional discomfort in the leg or hip muscles. Typically, complaints are provoked by walking and resolve after a brief rest. These symptoms limit walking ability leading to functional disability in daily life. Treatment of IC aims at reducing symptoms and thereby improving walking capacity and health-related quality of life (QoL).

Why are we doing this research?

The primary treatment for patients with intermittent claudication is Supervised Exercise Therapy (SET). This is exercise therapy conducted by a physical therapist. This therapy can increase the pain-free walking distance. An additional benefit from this therapy is the attention for unhealthy lifestyle factors, like smoking.

The narrowing of the lower limp arteries are often located in two places: around the hip (aortoiliac) and/or around the knee (femoropopliteal). Some clinici argue that for patients with aortoiliac disease a lower threshold to initiate invasive treatment is warranted. However, this has not been scientifically proved yet.

The aim of this study is to determine of SET outcome is affected by stenosis location.

Want to participate?

See the information on this page about participation in the study.  Also, discuss with your vascular surgeon if you’re a candidate for participation.