Inclusion Criteria

To be eligible to participate in this study, a subject must meet all of the following criteria:

  • IC due to PAD (Fontaine 2, Rutherford I-III)
  • Ankle-Brachial Index <0.9 or drop in ABI > 0.15 after an exercise test.
  • Candidate for SET as a primary treatment, at the discretion of the treating vascular surgeon.
  • Recent or planned imaging of the aortoiliac and femoropopliteal tract (within 6 months of SET initiation): either color Duplex Scanning (hemodynamically significant stenosis defined as a PSV ratio ≥ 2.5 or EDV ≥0.6 m/s) or MRA/CTA (>50% stenosis considered hemodynamically significant).
  • Signed informed consent form.

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded from participation in this study:

  • Advanced PAD beyond IC (i.e. ischemic rest pain and/or ulcers, Fontaine >II, Rutherford 4-6).
  • High probability of non-adherence to physician’s, or physical therapist’s follow-up requirements.
  • Current participation in a concurrent trial that may confound study results.
  • Vascular intervention as primary treatment, at the discretion of the treating vascular surgeon.
  • Prior SET, performed in accordance with the guidelines of the Dutch Society for Physical therapists, in the previous 12 months.
  • Prior revascularization in the lower-extremities in the previous 12 months.
  • Neurogenic-, venous- and/or orthopedic claudication.